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Frontiers | Sinomenine in cerebral ischemia: mechanisms, delivery strategies, and the emerging multifunctional biomaterials of the bone–brain axis
186 It has been observed that genera under Clostridiales are enriched in immunomodulatory subtype among TNBC patients, with high levels of its associated metabolite trimethylamine N-oxide (TMAO)
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These alterations in the composition or quantity of the NFκB dimer have been found to alter downstream target gene expression, contributing, in some cells, to increased expression of pro-inflammatory genes and a pro-apoptotic environment (170, 197, 275)
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