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Other cytokines, such as TGF-β, MCP-1, ICAM, and HO-1, also contribute to CIS nephrotoxicity [ 62 , 63 ]
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In its warning, the IAFF said glutathione is being marketed to firefighters as a way to remove toxins, but “there are no published scientific studies providing evidence that it reduces PFAS levels or oxidative stress associated with firefighters’ occupational exposures.” The union added that supplements can carry unexpected risks, noting that previous clinical trials of seemingly routine supplements have found increased disease risks in some groups
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