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1 Common Signs and Symptoms of Cyanide and Carbon Monoxide Poisoning 1,5 Recognizing Cyanide Poisoning in Smoke-Inhalation Victims Cyanide poisoning in smoke-inhalation victims should be suspected if the following manifestations are present 1* : Exposure to fire or smoke in an enclosed area Soot around the mouth, nose, or back of mouth Altered mental status (e.g., confusion, disorientation) *List may not be comprehensive Also indicative of cyanide poisoning is a plasma lactate concentration ≥10 mmol/L (a value higher than that typically listed in the table above of signs and symptoms of isolated cyanide poisoning because carbon monoxide associated with smoke inhalation also contributes to lactic acidemia)