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US9475854B2 - Lead compound for otoprotection: targeting HGF signaling with dihexa - Google Patents Lead compound for otoprotection: targeting HGF signaling with dihexa Download PDF Info Publication number US9475854B2 US9475854B2 US14/720,061 US201514720061A US9475854B2 US 9475854 B2 US9475854 B2 US 9475854B2 US 201514720061 A US201514720061 A US 201514720061A US 9475854 B2 US9475854 B2 US 9475854B2 Authority US United States Prior art keywords dihexa hgf amino acid isoleucine tyrosine Prior art date Legal status (The legal status is an assumption and is not a legal conclusion
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It promotes new blood vessel formation, stimulates keratinocyte and fibroblast migration into wound sites, and modulates the inflammatory response by reducing local levels of inflammatory cytokines — all critical to healing after oral surgical procedures
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