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Frataxin deficiency induces Schwann cell inflammation and death
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Active vitamin D (1,25 dihydroxyvitamin D) downregulates pro-inflammatory cytokines such as interleukin 6 (IL 6) and tumor necrosis factor α (TNF α) while enhancing anti-inflammatory mediators, including IL 4 and IL 10, thereby contributing to attenuation of placental inflammation and oxidative stress [117,118]
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