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Then, the sugar‐phosphate backbone is cleaved by AP endonuclease 1 (APE1) activity, and the resulting gap is filled with a single‐nucleotide match (short‐patch BER) or a few long matches (long‐patch BER) [87]
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In a mouse model of type 2 diabetes, MOTS-c administration increased antioxidant enzymes like SOD and CAT, protecting myocardial cells from oxidative stress [20]
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