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The selective ULK1/2 inhibitor, DCC-3116, synergizes with the KRASG12C inhibitor sotorasib to suppress KRAS-driven LC, whereas this combination has been assessed only in early preclinical stages and lacks predictive biomarkers for patient stratification (17)
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Samples were freeze-thawed followed by centrifugation at 14,000 rpm for 30 min at 4 °C
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