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All conditions were prepared as biological triplicates, phosphopeptides from 200 ΞΌg of whole-cell tryptic digests were enriched by Ti-IMAC and analyzed with 15-min gradients by DDA and DIA
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Compared with cytotoxic chemotherapy, both randomized and single-arm studies have established ICIs as transformative therapies in first-line and later-line settings, delivering durable remission and improving quality of life in a substantial subset of patients
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