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While ferroptosis remains the most iron-dependent form of cell death and displays the most pronounced amplification of lipid peroxidation, recent studies demonstrate that disturbances in iron homeostasis can also influence pyroptosis and necroptosis (Du et al., 2024)

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Transplanted cells secrete trophic factors that stimulate ECM synthesis to restore anabolic matrix production, counteract inflammatory mediators, and promote tissue homeostasis [52]