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Jonathan Downar at the University of Toronto refined a one-day accelerated TMS protocol using an antibiotic called deschloroetizolam (DCS) to induce neuroplasticity beforehand The standard multi-week protocol was already compressed down to five days, ten stimulations a day, but that’s still hard for most people to take off work for This newer version compresses it into a single day Tim experienced roughly a 90% reduction in his generalized anxiety and OCD symptoms lasting three to four months, and he’s met people with major depressive disorder who got 18 months of relief from just one day This is a part of a broader shift toward neuromodulation generally, not just psychedelics, “if the only tool you have is a hammer, everything starts to look like a nail” Historically, indigenous use of substances like ayahuasca was reserved for a tiny percentage of the population (specialists like the ethnobotanist or medicine man), not mass daily use Giving everyone psychedelics does not lead to world peace 53:25 – Cortisol As The Master Key Cortisol isn’t just a stress hormone, it’s an energy-deploying hormone that mobilizes glucose into the body Morning cortisol naturally rises to wake you up, and viewing bright light (ideally sunlight) first thing increases that morning spike by about 50% Exercise can triple or quadruple baseline cortisol at any point in the 24-hour cycle The real underlying principle, high cortisol in the morning sets up low cortisol and high melatonin at night, which is what actually produces great sleep This pattern holds true across kids, pregnant women, perimenopausal and menopausal women, and men, high morning cortisol, low evening and nighttime cortisol is the universal target This is proof the field of health and wellness is finally converging on real principles rather than a random pile of disconnected tips 56:24 – Peptides Demystified, GLP-1s, Growth Hormone, And BPC-157 Peptides represent people now mining the body itself for medicines, rather than isolating drugs from plants like pharma traditionally has (Dr