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For me (my opinion only), for any patients need to initiate metformin therapy for a first time, as a healthcare professionals, we should advise him (and the physician) to check calcium level before treatment, and monitor both B12 and calcium levels during the treatment
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Bleomycin-induced mouse fibrosis model and administration of anti-CD38 antibodies All animal studies were conducted in accordance with NIH guidelines for the care and use of laboratory animals and animal protocols were institutionally approved by the Animal Care and Use Committees of Northwestern University and the University of Michigan
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