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Other conditions Your doctor may recommend steroid injections for pain and inflammation caused by other health conditions, including: Autoimmune diseases, such as lupus and multiple sclerosis Back pain and inflamed spinal nerves, which can cause pain in your legs and arms Cervical radiculopathy, caused by a pinched nerve in your neck, which triggers pain in the neck, shoulders, arms, and hands Carpal tunnel syndrome, which is a pinched nerve in your wrist Trigger finger and trigger thumb (these cause a feeling of locking when you move your affected finger) What Are the Benefits of Steroid Injections