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Another related study showed that GB reduced ischemia-induced elevation of glutamate, aspartate, and glycine levels and increased extracellular γ-aminobutyric acid (GABA) levels, which means it altered the balance of excitatory and inhibitory amino acid levels in the brain and reduced excitotoxicity in the striatum of rats with MCAO, suggesting that GB ameliorated brain damage caused by cerebral ischemia-reperfusion and significantly reduced the rate of cerebral infarction in reperfused rats (Yang et al., 2011)