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Furthermore, the level of ADH3 enzyme is lower in the livers of Adh1 −/− mice compared with wild-type mice [24]
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By assessing the activity of Fe 2+ , TNF-α, IL-1β, IL-6, GPX4 and Nrf2 , it’s found that Gingerenone A can downregulate Fe 2+ , TNF-α, IL-1β, and IL-6 while upregulating GPX4 expression
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