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Therefore, it is important to use endothelial-derived factor inhibitors or to remove the endothelium to better understand the endothelial contribution to the effects of these hormones (Please see Table 15)
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Additionally, METTL3 is significantly overexpressed in RB tissues and cell lines, where it promotes RB cell proliferation, migration, invasion, and colony formation through the regulation of key components within the PI3K/AKT/mTOR signaling pathway
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