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Patients with a history of allergic reactions to injectable B-vitamin preparations should use caution

AMP

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In a model of Nrf2 −/− null mice subject to partial ischemia and reperfusion, the expression of several Nrf2-dependent genes was compromised, including GSTm1, NQO1, and GCL, resulting in the worsening of the redox state in comparison with livers from wild-type mice [218]