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c , Protein levels from cancer cell lines from DepMap’s CCLE (Proteomics GGT1: P19440 (n = 339), GGT5: P36269 (n = 108), GGT6: Q6P531 (n = 45), GGT7: Q9UJ14 (n = 375))
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Xanthohumol, isoxanthohumol, and 8-prenylnaringenin flavonones found in hops ( Humulus lupulus ) that exhibit anticancer activity are potent inhibitors of both AKR1B1 and AKR1B10 but do not affect the activity of AKR1A1 [185]
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