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Noteworthy findings from a mouse model of traumatic brain injury, a condition associated with increased oxidative stress in affected brain areas [153] and considered a risk factor for AD [154], underscore that melatonin treatment enhances the expression of nuclear factor erythroid 2-related factor 2 (Nrf2) [155] 142
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found that 41% (26 out of 63) of his patients presented with cutaneous changes as a primary symptom of vitamin B12 deficiency
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