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There were no or little inner hair cell (IHC) loss or outer hair cell (OHC) loss in the apical, middle or basal regions of the cochlea in both Gsr +/+ and Gsr -/- mice, and there were no differences in the numbers of IHCs or OHCs between WT and Gsr -/- mice (Fig 5A and 5B)

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After the occurrence of AP, the intestinal permeability increases, the intestinal flora is disordered, and bacterial translocation is likely to occur, resulting in “secondary infection,” so maintaining the structural and functional integrity of the intestinal barrier plays an important role in the prevention of local or systemic infectious complications of AP (Cen et al., 2018a)

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