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By use of GRK overexpression and knockdown methods in HEK293 cells, the same group recently reported DAMGO-induced phosphorylation of Thr370 and Ser375 is catalyzed by GRK2 and GRK3, but morphine-induced phosphorylation of Ser375 is predominantly mediated by GRK5 (Doll et al., 2012)
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[DOI] [PMC free article] [PubMed] [Google Scholar] 100.Cole S., Bhardwaj G., Gerlach J.H., Mackie J.E., Grant C.E., Almquist K.C., Stewart A.J., Kurz E.U., Duncan A.M., Deeley R.G
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