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Conversely, the role of PKC in internalization was ruled out using activators of this kinase in the locus coeruleus neurons expressing the FLAG-tagged MOR (Arttamangkul et al., 2007)
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Persistent oxidative stress drives irreversible oxidation to -SO2H or sulfonic-SO3H acids, disrupting protein function and promoting pathological outcomes (e.g., neurodegeneration and metabolic dysfunction) (15)
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